It typically takes about 20 days after mating for signs of pregnancy to become noticeable in a Cane Corso. At this stage, you might observe changes such as enlarged nipples and developing mammary glands. It's strongly recommended to take your dog to the vet for an ultrasound around the 30-day mark for a definitive confirmation.

Within about a week after mating, you may notice the Cane Corso female's vulva beginning to contract, accompanied by a small amount of dark brownish discharge and a decrease in appetite. Approximately 20 days post-breeding, indications like erect nipples and mammary gland development should become apparent. Around the one-month mark, you may notice abdominal swelling, drooping breasts, elastic nipples, gradually enlarging mammary glands, and even the possibility of milk production. In addition, there might be a rapid weight gain and increased frequency of urination. While these symptoms often suggest pregnancy, there's a chance of false pregnancy (pseudopregnancy). An ultrasound examination at about 30 days after breeding can confirm the presence of fetuses. If no fetuses are detected within 30 days after mammary development, it is likely that your dog is not pregnant. During pregnancy, it’s crucial to ensure your Cane Corso receives proper nutrition and maintain adequate levels of exercise.